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DeCS
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Descriptor English:
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RING Finger Domains
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Descriptor Spanish:
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Dominios RING Finger
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Descriptor Portuguese:
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Domínios RING Finger
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Synonyms English:
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Domains, RING Finger
RING Finger Domain
RING Finger Motif
RING Finger Motifs
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Tree Number:
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G02.111.570.820.709.275.500.985.500
G02.111.570.820.709.275.750.500.625
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Definition English:
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A zinc-binding domain defined by the sequence Cysteine-X2-Cysteine-X(9-39)-Cysteine-X(l-3)-His-X(2-3)-Cysteine-X2-Cysteine -X(4-48)-Cysteine-X2-Cysteine, where X is any amino acid. The RING finger motif binds two atoms of zinc, with each zinc atom ligated tetrahedrally by either four cysteines or three cysteines and a histidine. The motif also forms into a unitary structure with a central cross-brace region and is found in many proteins that are involved in protein-protein interactions. The acronym RING stands for Really Interesting New Gene. |
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History Note English:
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2008
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Allowable Qualifiers English:
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Record Number:
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52897
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Unique Identifier:
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D054829
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Occurrence in VHL:
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Similar:
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DeCS
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